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What is leukemia?

It moves fast, so it needs an urgent  diagnosis

Also known as blood cancer, leukemia starts in blood-forming tissue such as the bone marrow and blocks the body's ability to fight infection. It is the most common cancer of childhood, and treatment succeeds far more often when it is caught early.

A nurse talking with a child in treatment through a teddy bearA first in Türkiye

What is it?

What is leukemia (blood cancer)?

Leukemia is a cancer in which blood cells are produced abnormally and fail to mature. Normally blood is produced in the bone marrow, and healthy blood cells mature to meet the body's needs. In leukemia the bone marrow starts producing abnormal blood cells instead.

Leukemia falls into two main categories:

Acute leukemia: Young, abnormal blood cells that never complete the maturation process multiply rapidly. Patients can deteriorate quickly with this type.

Chronic leukemia: More mature blood cells are produced abnormally. It can progress more slowly and patients may have a longer life expectancy.

The exact cause of leukemia is not known, although certain genetic and environmental factors are thought to play a part.

Diagnosis and treatment rely on methods such as blood tests and bone marrow biopsy. Treatment varies with the type and stage of the leukemia and the patient's general health. Chemotherapy, bone marrow transplantation and targeted drug therapy are all commonly used.

For people diagnosed with leukemia, early detection and appropriate treatment can help bring the disease under control and improve quality of life. Even so, leukemia is a serious illness and treatment can be demanding. It matters that patients and their families work with medical specialists and accept support through the process.

A child in treatment with their doctorEarly diagnosis saves lives

It moves fast, so it needs an urgent diagnosis

Young, abnormal blood cells that never complete the maturation process multiply rapidly. Onset is often sudden and fast, with clinical signs and symptoms appearing within one to two months.

That is why a diagnosis has to be made quickly and treatment started as soon as possible. The most common type in children is acute lymphoblastic leukemia.

  • Paleness and fatigue
  • Recurring fever
  • Bruising and bleeding
  • Bone pain

2–8 November

Children with Leukemia Week.  An information booklet for schools and workplaces, classroom activities and “Remember a Child” campaign materials are ready.

Leukemia guide

Every question, answered topic by topic.

Diagnosis and treatment

How does the process work?

A diagnosis is made through a blood count and a bone marrow test. The treatment plan is set according to the child's age, the type of leukemia and the risk group; chemotherapy is the main treatment for most children. Some patients need a bone marrow transplant.

  • Blood count and examination

    If the full blood count is abnormal, the child is referred to paediatric haematology.

  • Bone marrow test

    The type and subgroup of leukemia are identified, and the treatment protocol follows from that.

  • Treatment and follow-up

    Chemotherapy, and where needed radiotherapy or a transplant, followed by long-term monitoring.

Bone marrow transplant

The first paediatric transplant in Türkiye was performed at our foundation.

The transplant carried out in the foundation's unit in 1989 was the first bone marrow transplant performed on a child in Türkiye. 199 transplants have been carried out since. A transplant replaces the patient's diseased bone marrow with healthy blood-forming cells; finding a tissue-matched donor is the most critical step in the process.

1,139

children treated with medication

25beds

children's ward opened in 1986

Opened by Prime Minister Turgut Özal and Semra Özal; the first institution to give children with leukemia private rooms.

199

bone marrow transplants

2firsts

children's ward opened in 1986

26 October 1989 — every paediatric transplant centre in the country traces its lineage back to here.

Becoming a donor

One blood sample, one chance for a child.

Healthy people aged 18 to 50 can register with the stem cell donor bank by giving a blood sample. Registering enters you into tissue matching; if you are a match, you will be contacted.

A Guide for Families

It is a blood cancer in which blood-forming cells multiply uncontrollably. It is the most common cancer of childhood, yet its causes are largely unknown; it does not arise from anything a family did wrong.